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* The economic results are not predictive for all patients and individual results may vary based upon a variety of inputs and patient-specific attributes. Results were simulated annual costs per living patient over a 10-year interval for 6 CLI management strategies, including primary amputation and purely endovascular intervention. Cost-effectiveness was quantified using incremental cost-effectiveness ratios (ICERs) in USD per quality-adjusted life-years (QALY) and cost-effectiveness acceptability curves. Model inputs consist of costs from the first 5-year intervals and were inflated from 2009 USD to 2017 USD.
